Hoʻopili i nā helu o ka metastasis cancer

ʻO ke ola maʻi ma muli o ka mahele pūnaewele. Ka Waihona: Nā National Institute of Health

I ka metastasis, hoʻokaʻawale nā ​​ʻokoʻa o ke kanesa i nā ʻōpū kū mua a kau i ke aʻa ma kekahi wahi o ke kahe wai. I mea e pālahalaha aku ai, nā mea hoʻoweliweli o nā metastatic i luna o ka endothelium-kahi keʻakeʻa o nā cell endothelial e waiho ana i ka ʻōnaehana uila e kaohi i ka hala ʻana o nā waihona o ke kahawai koko-he ʻano ka mea ʻaʻole i hoʻokō ʻia e nā cell non-metastatic.

Ma kahi papahana i paʻiʻia Hōʻike Pūnaewele, mea kākau mua ʻo Yamicia D. Connor, MD, PhD, he kamaʻilio ma ka Keʻena ʻO Obstetrics a me Gynecology ma Bet Israel Deaconess Medical Center (BIDMC), a me nā hoa hana, i ka hōʻike ʻana aku i nā mea pili ole metastatic, nā ʻāpana metastatic umauma i loaʻa hiki ke hoʻololi i ka hoʻohuli, hoʻopōmaikaʻi ʻia a ʻoi aku ka maikaʻi o ke kālai ʻana i ka endothelium a i loko o ke kahawai koko. Ma kahi o ka hōʻike ʻana i ka hoʻololi, ua hoʻokumu ʻia ka hui a i ka hoʻohālike e hōʻike i kēia pilina ma waena o ka metastatic a me hiki ke maʻalahi ka hoʻololi.

"Hōʻike kā mākou data e ʻoi aku ka maikaʻi o nā sel metastatic umauma, akā hiki iā lākou ke hoʻololi i ko lākou ʻano e kōkua ai , he laikini koʻikoʻi ka hoʻolaha ʻana i ka maʻi maʻi, "wahi a Connor. "Ke hōʻike nei ke noiʻi pehea e hiki ai i nā kumu makemakika ke hoʻohui pū ʻia me nā ʻōnaehana biology e hoʻolako a helu i nā ʻike koʻikoʻi ma ka biology cellular a i ʻole nā ​​hoʻokolohua hōʻoia i nā pahuhopu lāʻau."

Ke hoʻohana nei i kēia ʻano hana like matematika, hōʻike ʻia nā mea noiʻi ua palena iki kēia ʻano ma ka maʻi umauma maʻi a i ʻole nā ​​maʻi metastatic. Ma kahi haʻawina kaʻawale, ke ʻimi nei ʻo ka hui ʻo Connor inā ovarian like like paha me ka endothelium e like me nā ʻōpū o ka umauma maʻi.

"ʻO kēia mau mea ʻike i hāʻawi i kahi ala no ka hoʻokolokolo ʻana i ka hiki o ka metastatic tumor i kahi ʻōnaehana hoʻohālikelike 3-D," wahi a Toni Golen, MD, ka poʻokela poʻokela o ka Oihana Obstetrics a me Gynecology ma BIDMC, ʻaʻole i hoʻopili ʻia i ka noiʻi. "Hiki paha i kēia ke kumu no ka noiʻi e hiki mai ana e noiʻi inā e helu ana i ka hōʻiliʻili kino ʻana ma waena a me nā mea kelepona ʻē aʻe hiki ke hāʻawi i ka ʻike i ka ʻoihana o ka maʻi metastatic i hiki ke hoʻohana ʻia e alakaʻi i nā hoʻoholo no nā maʻi. "


Ka mea 'nui' i ka hoʻomaʻamaʻa metastasis


More 'ikepili:
Yamicia Connor et al, He moolelo matematika o ka hoʻopili ʻana i ka hopena o ka end-endothelial ma 3D co-culture, Hōʻike Pūnaewele (2019). DOI: 10.1038/s41598-019-44713-2

Kāhea:
Ke hōʻemi nei i ka helu helu metastasis (2019, Iulai 17)
ua kiʻiʻia mai ka 17 Iulai 2019
mai https://medicalxpress.com/news/2019-07-crunching-cancer-metastasis.html

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Uaʻike muaʻia kēiaʻatikala https://medicalxpress.com/news/2019-07-crunching-cancer-metastasis.html